A 24 year old right handed Pakistani woman who was eight weeks’ pregnant presented with a two day history of involuntary movements of her left arm, hand. According to Willson and Preece, the first description of chorea with onset during pregnancy (chorea gravidarum) was made by Horstius in The English. A pregnant woman, in her early 20s, presents with chorea following an emotional outburst. While the family members feel it to be a spirit.

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Pregnancy with abortive outcome Ectopic pregnancy Abdominal pregnancy Cervical pregnancy Interstitial pregnancy Ovarian pregnancy Heterotopic pregnancy Molar pregnancy Miscarriage Stillbirth.

Chorea gravidarum is considered a syndrome rather than a specific disease entity. Another condition associated with anti-basal ganglia antibodies”.

Chorea gravidarum – Wikipedia

Infobox medical condition new All articles with unsourced statements Articles with unsourced statements from May However, the scenario is different in developing countries like India where rheumatic fever still occurs frequently. The relation to rheumatic fever was strengthened by many studies that showed that women with normal pregnancies before rheumatic fever developed chorea in subsequent pregnancies. This finding, as well as the persistence of the movement disorder, uncommon in chorea gravidarum, 2 suggests that the chorea of the patient was related to some other cause, perhaps a stroke.

Chorea gravidarum is an uncommon condition characterized by involuntary movements, speaking alterations and in the affective status during first trimester pregnancy, the incidence is 1 by each pregnancies, it is self limiting and resolves when the pregnancy ends, most of the cases are idiopathic and the rest is associated to the antiphospholipid syndrome, rheumatic fever, thyrotoxicosis, systemic lupus erythematosus, syphilis, Huntington disease or induced by drugs.


Views Read Edit View history. The involuntary movements in her tongue and arms were neglected as the attendants took her to a local priest thinking it as an evil spirit in the hills.

The English translation of the Latin work provided in their article, however, indicates that the woman described by Horstius in fact developed chorea at the puerperium. There was no history of psychiatric illnesses in the past. There was no family history of any neurological disease.

The present patient was a case of rheumatic chorea without carditis with previous history of rheumatism but she was at risk of developing rheumatic heart disease in future. Patients with Sydenham’s chorea are at risk for the development of rheumatic carditis particularly mitral stenosis and to prevent this, a regimen of daily penicillin prophylaxis should be instituted and maintained.

Antistreptolysins antibodies ofPCR 1: Author information Copyright and License information Disclaimer. There were no cerebellar signs and signs of meningeal irritation.

Sensory system and all cranial nerve examination were normal with flexor plantar response. D ICD – Brain Encephalitis Viral encephalitis Herpesviral encephalitis Limbic encephalitis Encephalitis lethargica Cavernous sinus thrombosis Brain abscess Amoebic.

BSL compiled the case report and submitted it online. J Child Neurol ; From Wikipedia, the free encyclopedia.

Chorea gravidarum: a rarity in West still haunts pregnant women in the East

A pregnant woman, in her early 20s, presents with chorez following an emotional outburst. Create a free personal account to make a comment, download free article PDFs, sign up for alerts and more.

The choreic movements may be caused by ischaemia or enhanced dopaminergic sensitivity mediated by increased female hormones during pregnancy. It is not an causal or pathologically distinct entity but a generic term for chorea of any cause starting during pregnancy. Her symptoms had subsided after taking gravidaruk antibiotics and analgesics from a local health centre.


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Chorea gravidarum

AS is the obstetrician who carefully assisted in the patient delivering a healthy fetus. However, she denied any history of taking long-term injectable penicillin for the same. Insomnia Hypersomnia Sleep apnea Obstructive Congenital central hypoventilation syndrome Narcolepsy Cataplexy Kleine—Levin Circadian rhythm sleep disorder Advanced sleep phase disorder Delayed sleep phase disorder Nonhour sleep—wake disorder Jet lag.

Treatment The patient was admitted in a quiet isolated ward and given one dose of benzathine penicillin, iron and calcium supplements were given along with multivitamins. According to Willson and Preece, 1 the first description of chorea with onset during pregnancy chorea gravidarum was made by Horstius in It is a complication of pregnancy which can be associated with yravidarum and its xhorea upon the basal ganglia.

A patient developed this chorea with no definite evidence of previous Sydenham’s chorea or recent streptococcal infections, but had anti-basal gavidarum antibodiessuggesting immunological basis for the pathophysiology of this chorea.

Gravidaruum pathogenetic mechanisms for chorea gravidarum have been offered, but none have been proven. Concomitant conditions Diabetes mellitus Systemic lupus erythematosus Thyroid disorders Maternal death Sexual activity during pregnancy.